Diverticular disease: a clinical review

Abstract

Diverticular disease is an umbrella term encompassing symptomatic diverticulosis, uncomplicated and complicated diverticulitis. The presence of diverticula increases with age, affecting up to 70% of the population by 80 years of age. It is associated with a significant economic burden in terms of healthcare costs, hospitalisation, and resource use. Although mortality from non-complicated diverticulosis is extremely rare, morbidity and mortality risk increase ten-fold with complications such as perforation or fistula. This article will examine diverticular disease, its pathogenesis, symptoms and complications. Additionally, the surgical and non-surgical treatment options will be discussed, including the role of antibiotics.