Avoiding chemotherapy for advanced nononcogene addicted NSCLC overexpressing PD-L1: Rule or option?

Author:

Pilotto Sara,Carbognin Luisa,Rossi Antonio,Tortora Giampaolo,Bria Emilio

Funder

Italian Association for Cancer Research

Publisher

Elsevier BV

Subject

Oncology,Hematology

Reference12 articles.

1. The biology and management of non-small cell lung cancer;Herbst;Nature,2018

2. Keytruda (pembrolizumab) FDA Approval History. Available at: https://www.drugs.com/history/keytruda.html (Accessed July 1, 2018).

3. European Medicines Agency - Find Medicine - Keytruda. Available at: http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/003820/human_med_001886.jsp&mid=WC0b01ac058001d124 (Accessed July 1, 2018).

4. Pembrolizumab versus chemotherapy for PD-L1-positive non-small-cell lung cancer;Reck;N Engl J Med,2016

5. Pembrolizumab (pembro) versus platinum-based chemotherapy (chemo) as first-line therapy for advanced/metastatic NSCLC with a PD-L1 tumor proportion score (TPS) ≥ 1%: Open-label, phase 3 KEYNOTE-042 study;Lopes;J Clin Oncol,2018

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