Differential effects of SB 242235, a selective p38 mitogen-activated protein kinase inhibitor, on IL-1 treated bovine and human cartilage/chondrocyte cultures

Author:

Badger A.M,Roshak A.K,Cook M.N,Newman-Tarr T.M,Swift B.A,Carlson K,Connor J.R,Lee J.C,Gowen M,Lark M.W,Kumar S

Publisher

Elsevier BV

Subject

Orthopedics and Sports Medicine,Biomedical Engineering,Rheumatology

Reference60 articles.

1. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis;Lee;Nature,1994

2. 2,4,5-Triarylimidazole inhibitors of IL-1 biosynthesis;Gallagher;Bioorganic Med Chem Letters,1995

3. Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function;Badger;J Pharm Exp Ther,1996

4. A MAP kinase targeted by endotoxin and in mammalian cells;Han;Science,1994

5. Identification of a novel protein kinase cascade stimulated by chemical stress and heat shock which activates MAP kinase-activated protein MAPKAP kinase-2 and induces phosphorylation of the small heat shock proteins;Rouse;Cell,1994

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