Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

Author:

Archambault Alexi N.ORCID,Su Yu-RuORCID,Jeon Jihyoun,Thomas MintaORCID,Lin Yi,Conti David V.,Win Aung KoORCID,Sakoda Lori C.ORCID,Lansdorp-Vogelaar Iris,Peterse Elisabeth F.P.ORCID,Zauber Ann G.,Duggan David,Holowatyj Andreana N.ORCID,Huyghe Jeroen R.ORCID,Brenner Hermann,Cotterchio Michelle,Bézieau Stéphane,Schmit Stephanie L.ORCID,Edlund Christopher K.,Southey Melissa C.ORCID,MacInnis Robert J.ORCID,Campbell Peter T.,Chang-Claude JennyORCID,Slattery Martha L.ORCID,Chan Andrew T.,Joshi Amit D.,Song Mingyang,Cao Yin,Woods Michael O.,White Emily,Weinstein Stephanie J.ORCID,Ulrich Cornelia M.ORCID,Hoffmeister Michael,Bien Stephanie A.ORCID,Harrison Tabitha A.ORCID,Hampe JochenORCID,Li Christopher I.,Schafmayer Clemens,Offit Kenneth,Pharoah Paul D.ORCID,Moreno VictorORCID,Lindblom Annika,Wolk AlicjaORCID,Wu Anna H.,Li Li,Gunter Marc J.,Gsur AndreaORCID,Keku Temitope O.ORCID,Pearlman RachelORCID,Bishop D. TimothyORCID,Castellví-Bel Sergi,Moreira Leticia,Vodicka Pavel,Kampman EllenORCID,Giles Graham G.ORCID,Albanes Demetrius,Baron John A.,Berndt Sonja I.,Brezina StefanieORCID,Buch Stephan,Buchanan Daniel D.ORCID,Trichopoulou Antonia,Severi GianlucaORCID,Chirlaque María-Dolores,Sánchez Maria-José,Palli DomenicoORCID,Kühn Tilman,Murphy Neil,Cross Amanda J.ORCID,Burnett-Hartman Andrea N.,Chanock Stephen J.,de la Chapelle AlbertORCID,Easton Douglas F.,Elliott FayeORCID,English Dallas R.ORCID,Feskens Edith J.M.ORCID,FitzGerald Liesel M.ORCID,Goodman Phyllis J.,Hopper John L.,Hudson Thomas J.ORCID,Hunter David J.,Jacobs Eric J.,Joshu Corinne E.ORCID,Küry Sébastien,Markowitz Sanford D.,Milne Roger L.ORCID,Platz Elizabeth A.ORCID,Rennert GadORCID,Rennert Hedy S.,Schumacher Fredrick R.ORCID,Sandler Robert S.,Seminara Daniela,Tangen Catherine M.,Thibodeau Stephen N.,Toland Amanda E.ORCID,van Duijnhoven Franzel J.B.,Visvanathan Kala,Vodickova Ludmila,Potter John D.ORCID,Männistö Satu,Weigl Korbinian,Figueiredo Jane,Martín Vicente,Larsson Susanna C.ORCID,Parfrey Patrick S.,Huang Wen-YiORCID,Lenz Heinz-Josef,Castelao Jose E.,Gago-Dominguez ManuelaORCID,Muñoz-Garzón Victor,Mancao Christoph,Haiman Christopher A.,Wilkens Lynne R.,Siegel Erin,Barry ElizabethORCID,Younghusband Ban,Van Guelpen BethanyORCID,Harlid SophiaORCID,Zeleniuch-Jacquotte Anne,Liang Peter S.ORCID,Du Mengmeng,Casey Graham,Lindor Noralane M.,Le Marchand Loic,Gallinger Steven J.,Jenkins Mark A.ORCID,Newcomb Polly A.,Gruber Stephen B.,Schoen Robert E.ORCID,Hampel HeatherORCID,Corley Douglas A.,Hsu Li,Peters Ulrike,Hayes Richard B.ORCID

Funder

National Cancer Institute

National Institutes of Health

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology

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