Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase-3 Expression

Author:

Kuo Wei-TingORCID,Shen LeORCID,Zuo Li,Shashikanth Nitesh,Ong Ma.Lora Drizella M.,Wu Licheng,Zha Juanmin,Edelblum Karen L.ORCID,Wang Yitang,Wang Yingmin,Nilsen Steven P.,Turner Jerrold R.ORCID

Funder

National Institutes of Health

Harvard Digestive Disease Center

National Science Foundation of China

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology

Reference45 articles.

1. Occludin: a novel integral membrane protein localizing at tight junctions;Furuse;J Cell Biol,1993

2. Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures;Furuse;J Cell Sci,1996

3. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton;Fanning;J Biol Chem,1998

4. Occludin S471 Phosphorylation Contributes to Epithelial Monolayer Maturation;Bolinger;Mol Cell Biol,2016

5. Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents its interaction with ZO-1 and destabilizes its assembly at the tight junctions;Elias;J Biol Chem,2009

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