SETDB1 Inhibits p53-Mediated Apoptosis and Is Required for Formation of Pancreatic Ductal Adenocarcinomas in Mice-Reference-Cited by-同舟云学术

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SETDB1 Inhibits p53-Mediated Apoptosis and Is Required for Formation of Pancreatic Ductal Adenocarcinomas in Mice

Published:2020-08 Issue:2 Volume:159 Page:682-696.e13
ISSN:0016-5085
Container-title:Gastroenterology
language:en
Short-container-title:Gastroenterology

Author:

Ogawa Satoshi^ORCID,Fukuda Akihisa,Matsumoto Yoshihide,Hanyu Yuta,Sono Makoto,Fukunaga Yuichi,Masuda Tomonori,Araki Osamu,Nagao Munemasa^ORCID,Yoshikawa Takaaki,Goto Norihiro,Hiramatsu Yukiko^ORCID,Tsuda Motoyuki,Maruno Takahisa,Nakanishi Yuki,Hussein Mohammed S.,Tsuruyama Tatsuaki,Takaori Kyoichi,Uemoto Shinji,Seno Hiroshi

Funder

Mochida Memorial Foundation for Medical and Pharmaceutical Research

Mitsubishi Foundation

Uehara Memorial Foundation

Takeda Science Foundation

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Princess Takamatsu Cancer Research Fund

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology

Reference37 articles.

1. Pancreatic adenocarcinoma;Ryan;N Engl J Med,2014

2. DNA methylation screening identifies driver epigenetic events of cancer cell survival;De Carvalho;Cancer Cell,2012

3. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase;Kubicek;Mol Cell,2007

4. EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations;McCabe;Nature,2012

5. Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming;Koutsioumpa;Gut,2018

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1. SETDB1, an H3K9-specific methyltransferase: An attractive epigenetic target to combat cancer;Drug Discovery Today;2024-05

2. Comparative transcriptomic analysis reveals the molecular changes of acute pancreatitis in experimental models;World Journal of Gastroenterology;2024-04-14

3. SETDB1: Progress and prospects in cancer treatment potential and inhibitor research;Bioorganic Chemistry;2024-04

4. SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer;Journal of Ovarian Research;2024-02-05

5. SETDB1 as a cancer target: challenges and perspectives in drug design;RSC Medicinal Chemistry;2024

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