Mucin 5AC Serves as the Nexus for β-Catenin/c-Myc Interplay to Promote Glutamine Dependency During Pancreatic Cancer Chemoresistance

Author:

Ganguly Koelina,Bhatia Rakesh,Rauth Sanchita,Kisling Andrew,Atri Pranita,Thompson Christopher,Vengoji Raghupathy,Ram Krishn Shiv,Shinde Dhananjay,Thomas Vinai,Kaur Sukhwinder,Mallya Kavita,Cox Jesse L.,Kumar Sushil,Batra Surinder K.

Funder

National Institutes of Health

National Institute of Allergy and Infectious Diseases

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology

Reference49 articles.

1. Pancreatic Cancer Action Network. Available at: http://media.pancan.org/FILES/MediaFactSheet_RGB.pdf.

2. Therapeutic developments in pancreatic cancer: current and future perspectives;Neoptolemos;Nat Rev Gastroenterol Hepatol,2018

3. Role of oncogenic KRAS in the diagnosis, prognosis and treatment of pancreatic cancer;Buscail;Nat Rev Gastroenterol Hepatol,2020

4. Oncogenic KRAS confers chemoresistance by upregulating NRF2;Tao;Cancer Res,2014

5. Secretory mucin 5AC promotes neoplastic progression by augmenting KLF4-mediated pancreatic cancer cell stemness;Ganguly;Cancer Res,2021

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