FXR Isoforms Control Different Metabolic Functions in Liver Cells via Binding to Specific DNA Motifs-Reference-Cited by-同舟云学术

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FXR Isoforms Control Different Metabolic Functions in Liver Cells via Binding to Specific DNA Motifs

Published:2020-11 Issue:5 Volume:159 Page:1853-1865.e10
ISSN:0016-5085
Container-title:Gastroenterology
language:en
Short-container-title:Gastroenterology

Author:

Ramos Pittol Jose Miguel,Milona Alexandra,Morris Imogen,Willemsen Ellen C.L.,van der Veen Suzanne W.,Kalkhoven Eric,van Mil Saskia W.C.

Funder

H2020 Marie Skłodowska-Curie Actions

FP7 People: Marie-Curie Actions

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology

Reference50 articles.

1. Identification of a nuclear receptor for bile acids;Makishima;Science,1999

2. Bile acids: natural ligands for an orphan nuclear receptor;Parks;Science,1999

3. Endogenous bile acids are ligands for the nuclear receptor FXR/BAR;Wang;Mol Cell,1999

4. Farnesoid X receptor: a “homeostat” for hepatic nutrient metabolism;Massafra;Biochim Biophys Acta Mol Basis Dis,2018

5. Farnesoid X receptor activation promotes hepatic amino acid catabolism and ammonium clearance in mice;Massafra;Gastroenterology,2017

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2. Unlocking therapeutic potential: exploring cross-talk among emerging nuclear receptors to combat metabolic dysfunction in steatotic liver disease;npj Metabolic Health and Disease;2024-07-03

3. Role of FXR in the development of NAFLD and intervention strategies of small molecules;Archives of Biochemistry and Biophysics;2024-07

4. Nuclear receptors: pathophysiological mechanisms and drug targets in liver disease;Gut;2024-06-11

5. Bile acid metabolism and signaling in health and disease: molecular mechanisms and therapeutic targets;Signal Transduction and Targeted Therapy;2024-04-26

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