Loss of P53 Function Activates JAK2–STAT3 Signaling to Promote Pancreatic Tumor Growth, Stroma Modification, and Gemcitabine Resistance in Mice and Is Associated With Patient Survival
Author:
Publisher
Elsevier BV
Subject
Gastroenterology,Hepatology
Reference45 articles.
1. Pancreatic cancer;Hidalgo;N Engl J Med,2010
2. STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis;Corcoran;Cancer Res,2011
3. Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling;Jones;J Clin Invest,2011
4. Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer;Lesina;Cancer Cell,2011
5. STATs in cancer inflammation and immunity: a leading role for STAT3;Yu;Nat Rev Cancer,2009
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