HIF-2 in Cancer-Associated Fibroblasts Polarizes Macrophages and Creates an Immunosuppressive Tumor Microenvironment in Pancreatic Cancer
Author:
Publisher
Elsevier BV
Subject
Gastroenterology,Hepatology
Reference14 articles.
1. Pancreatic cancer stroma: an update on therapeutic targeting strategies;Hosein;Nat Rev Gastroenterol Hepatol,2020
2. Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion;Murray;Cell Rep,2022
3. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival;Ozdemir;Cancer Cell,2014
4. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer;Olive;Science,2009
5. Type I collagen deletion in alphaSMA(+) myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer;Chen;Cancer Cell,2021
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1. A target map of clinical combination therapies in oncology: an analysis of clinicaltrials.gov;Discover Oncology;2023-08-21
2. Molecular and metabolic regulation of immunosuppression in metastatic pancreatic ductal adenocarcinoma;Molecular Cancer;2023-07-24
3. Prognostic value of tumor-associated N1/N2 neutrophil plasticity in patients following radical resection of pancreas ductal adenocarcinoma;Journal for ImmunoTherapy of Cancer;2022-12
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