Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity

Author:

Liu Zhang-Xu,Govindarajan Sugantha,Kaplowitz Neil

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology

Reference65 articles.

1. Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism;Mitchell;J Pharmacol Exp Ther,1973

2. N-acetyl-p-benzoquinone imine;Dahlin;Proc Natl Acad Sci U S A,1984

3. Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione;Mitchell;J Pharmacol Exp Ther,1973

4. Role of CYP2E1 in the hepatotoxicity of acetaminophen;Lee;J Biol Chem,1996

5. Acetaminophen toxicity results in site-specific mitochondrial damage in isolated mouse hepatocytes;Burcham;J Biol Chem,1991

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