Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor-α-induced apoptosis in cultured mouse hepatocytes

Author:

Nagai Hidenari,Matsumaru Katsuhiko,Feng Guoping,Kaplowitz Neil

Funder

USC-UCLA Research Center Alcoholic Liver and Pancreatic Disease

Isolation and culture of mouse hepatocytes were performed by the Cell Culture Core of the USC Research Center for Liver Diseases

Publisher

Wiley

Subject

Hepatology

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4. Inhibition of caspase induces a switch from apoptosis to necrosis;Lemaire;FEBS Lett,1998

5. Mechanisms of hepatic toxicity v. necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis;Lemasters;Am J Physiol,1999

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