Hematopoietic cell transplant for acute myeloid leukemia and myelodysplastic syndrome: conditioning regimen intensity-Reference-Cited by-同舟云学术

Hematopoietic cell transplant for acute myeloid leukemia and myelodysplastic syndrome: conditioning regimen intensity

Published:2018-08-22 Issue:16 Volume:2 Page:2095-2103
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Eapen Mary¹,Brazauskas Ruta²,Hemmer Michael¹,Perez Waleska S.¹,Steinert Patricia¹,Horowitz Mary M.¹,Deeg H. Joachim³

Affiliation:

1. Center for International Blood and Marrow Transplant Research, Department of Medicine, and

2. Division of Biostatistics, Institute for Health and Society, Medical College of Wisconsin, Milwaukee, WI; and

3. Fred Hutchinson Cancer Research Center, Seattle, WA

Abstract

Key Points Bu4/Cy, Flu/Bu4, and Flu/Mel are optimal regimens for patients with AML in clinical remission or those with MDS. Flu/Mel, considered a less-intense regimen, is ideal for less fit patients.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/16/2095/881813/advances021980.pdf

Reference26 articles.

1. Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic haematopoietic stem cell transplantation for patients older than 50 years of age with acute myeloblastic leukaemia: a retrospective survey from the Acute Leukemia Working Party (ALWP) of the European group for Blood and Marrow Transplantation (EBMT);Aoudjhane;Leukemia,2005

2. Myeloablative vs nonmyeloablative allogeneic transplantation for patients with myelodysplastic syndrome or acute myelogenous leukemia with multilineage dysplasia: a retrospective analysis;Scott;Leukemia,2006

3. Allogeneic hematopoietic stem-cell transplantation in AML and MDS using myeloablative versus reduced-intensity conditioning: the role of dose intensity;Shimoni;Leukemia,2006

4. Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes;Martino;Blood,2006

5. Impact of conditioning regimen intensity on outcome of allogeneic hematopoietic cell transplantation for advanced acute myelogenous leukemia and myelodysplastic syndrome;Alyea;Biol Blood Marrow Transplant,2006

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