Invasive fungal infections after CLAG-M/CLAG chemotherapy for acute myeloid leukemia and high-grade myeloid neoplasms

Author:

Lindsay Julian12ORCID,Walti Carla S.13ORCID,Halpern Anna B.45,Xie Hu4,Chung E. Lisa1ORCID,Schonhoff Kelda G.4,Huebner Emily M.1,Cheng Guang-Shing146ORCID,Kimball Louise E.1,Leisenring Wendy M.1ORCID,Greenwood Matthew78ORCID,Chen Sharon C. -A.29,Kong David C. M.101112,Slavin Monica A.21314,Boeckh Michael115,Fredricks David N.115,Liu Catherine115,Pergam Steven A.115ORCID,Walter Roland B.451617ORCID,Hill Joshua A.115ORCID

Affiliation:

1. 1Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA

2. 2National Centre for Infection in Cancer, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia

3. 3Division of Infectious Diseases and Hospital Epidemiology, Basel University Hospital, Basel, Switzerland

4. 4Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA

5. 5Division of Hematology, Department of Medicine, University of Washington, Seattle, WA

6. 6Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Washington, Seattle, WA

7. 7Haematology Department, Royal North Shore Hospital, Sydney, NSW, Australia

8. 8Northern Blood Research Centre, Kolling Institute of Medical Research, The University of Sydney, Sydney, Australia

9. 9Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, New South Wales Health Pathology, Westmead Hospital, The University of Sydney, Sydney, NSW, Australia

10. 10National Health and Medical Research Council National Centre for Antimicrobial Stewardship at The Peter Doherty Institute for Infections and Immunity, Parkville, VIC, Australia

11. 11Centre for Medicine Use and Safety, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia

12. 12Pharmacy Department, Grampians Health, Ballarat, VIC, Australia

13. 13Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Australia

14. 14Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia

15. 15Division of Allergy & Infectious Diseases, University of Washington, Seattle, WA

16. 16Department of Laboratory Medicine & Pathology, University of Washington, Seattle, WA

17. 17Department of Epidemiology, University of Washington, Seattle, WA

Publisher

American Society of Hematology

Subject

Hematology

Reference19 articles.

1. Antimicrobial prophylaxis for adult patients with cancer-related immunosuppression: ASCO and IDSA clinical practice guideline update;Taplitz;J Clin Oncol,2018

2. European guidelines for primary antifungal prophylaxis in adult haematology patients: summary of the updated recommendations from the European Conference on Infections in Leukaemia;Maertens;J Antimicrob Chemother,2018

3. Phase 1/2 trial of GCLAM with dose-escalated mitoxantrone for newly diagnosed AML or other high-grade myeloid neoplasms;Halpern;Leukemia,2018

4. Phase I/II trial of cladribine, high-dose cytarabine, mitoxantrone, and G-CSF with dose-escalated mitoxantrone for relapsed/refractory acute myeloid leukemia and other high-grade myeloid neoplasms;Halpern;Haematologica,2019

5. Comparison of high-dose cytarabine, mitoxantrone, and pegaspargase (HAM-pegA) to high-dose cytarabine, mitoxantrone, cladribine, and filgrastim (CLAG-M) as first-line salvage cytotoxic chemotherapy for relapsed/refractory acute myeloid leukemia;Patzke;J Clin Med,2020

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