Coordination of platelet agonist signaling during the hemostatic response in vivo-Reference-Cited by-同舟云学术

Coordination of platelet agonist signaling during the hemostatic response in vivo

Published:2017-12-21 Issue:27 Volume:1 Page:2767-2775
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Shen Jian¹,Sampietro Sara²,Wu Jie²,Tang Juan³,Gupta Shuchi²,Matzko Chelsea N.²,Tang Chaojun¹,Yu Ying³,Brass Lawrence F.²,Zhu Li¹,Stalker Timothy J.²

Affiliation:

1. Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology, MOH Key Laboratory of Thrombosis and Hemostasis, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Soochow University, Suzhou, China;

2. Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; and

3. Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Shanghai, China

Abstract

Key Points Coordinated thromboxane A2 and ADP/P2Y12 signaling is required for platelet accumulation in the outer shell region of hemostatic plugs. Platelet activation within the hemostatic plug core region is predominantly mediated by thrombin.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/1/27/2767/879388/advances009498.pdf

Reference33 articles.

1. Impaired activation of murine platelets lacking G alpha(i2);Jantzen;J Clin Invest,2001

2. Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors;Paul;J Biol Chem,1999

3. Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation;Jin;Proc Natl Acad Sci USA,1998

4. Signal transduction during platelet plug formation;Brass,2013

5. Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs;Yang;Proc Natl Acad Sci USA,2000

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Revitalizing female fertility: platelet-rich plasma – hype or hope?;Reproductive BioMedicine Online;2024-08

2. Study on the Mechanism of the Adrenaline-Evoked Procoagulant Response in Human Platelets;International Journal of Molecular Sciences;2024-03-05

3. Dual antithrombotic therapy dose-dependently alters hemostatic plug structure and function;Journal of Thrombosis and Haemostasis;2023-12

4. A comprehensive review of the ten main platelet receptors involved in platelet activity and cardiovascular disease;American Journal of Blood Research;2023

5. GRK2 regulates ADP signaling in platelets via P2Y1 and P2Y12;Blood Advances;2022-08-04