Immunoadsorption and autologous transplantation for life-threatening primary antiphospholipid syndrome-Reference-Cited by-同舟云学术

Immunoadsorption and autologous transplantation for life-threatening primary antiphospholipid syndrome

Published:2019-09-10 Issue:17 Volume:3 Page:2664-2667
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Angelillo-Scherrer Anne¹²^ORCID,Mansouri Taleghani Behrouz¹,Förger Frauke³,Baerlocher Gabriela M.¹²,Pabst Thomas⁴,Pöllinger Alexander⁵,Banz Yara⁶,Geiser Thomas⁷,Kremer Hovinga Johanna A.¹²^ORCID,Rovó Alicia¹

Affiliation:

1. Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,

2. Department for BioMedical Research,

3. Department of Rheumatology, Immunology, Allergology, Inselspital, Bern University Hospital,

4. Department of Medical Oncology, Inselspital, Bern University Hospital,

5. Department of Diagnostic, Interventional and Pediatrics Radiology, Bern University Hospital,

6. Institute of Pathology, and

7. Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

Abstract

Key Points Reduction of APL antibodies by immunoadsorption may be a lifesaving therapy for the management of DAH with high titer of APL antibodies. Autologous HSCT may be a valid treatment option in patients with primary APS and no response to standard immunosuppressive therapy.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/3/17/2664/1716282/advancesadv2019000465.pdf

Reference21 articles.

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2. Primary antiphospholipid syndrome-associated diffuse alveolar hemorrhage;Cartin-Ceba;Arthritis Care Res (Hoboken),2014

3. Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients;Cervera;Arthritis Rheum,2002

4. Antiphospholipid antibodies as a cause of pulmonary capillaritis and diffuse alveolar hemorrhage: a case series and literature review;Deane;Semin Arthritis Rheum,2005

5. A therapeutic challenge: catastrophic anti-phospholipid syndrome with diffuse alveolar haemorrhage;Martis;Immunol Res,2015