Safety of allogeneic hematopoietic cell transplant in adults after CD19-targeted CAR T-cell therapy-Reference-Cited by-同舟云学术

Safety of allogeneic hematopoietic cell transplant in adults after CD19-targeted CAR T-cell therapy

Published:2019-10-22 Issue:20 Volume:3 Page:3062-3069
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Shadman Mazyar¹²,Gauthier Jordan¹,Hay Kevin A.³^ORCID,Voutsinas Jenna M.¹,Milano Filippo¹²,Li Ang¹²^ORCID,Hirayama Alexandre V.¹^ORCID,Sorror Mohamed L.¹²,Cherian Sindhu⁴,Chen Xueyan⁴,Cassaday Ryan D.¹²^ORCID,Till Brian G.¹²,Gopal Ajay K.¹²^ORCID,Sandmaier Brenda M.¹²^ORCID,Maloney David G.¹²,Turtle Cameron J.¹²^ORCID

Affiliation:

1. Clinical Research Division, Fred Hutch, Seattle, WA;

2. Department of Medicine, University of Washington, Seattle, WA;

3. Department of Medicine, University of British Columbia, Vancouver, BC, Canada; and

4. Department of Laboratory Medicine, University of Washington, Seattle, WA

Abstract

Key Points The toxicity of allo-HCT in patients with prior CAR-T therapy was not higher than what is expected in these high-risk patients. In ALL patients, there seems to be a benefit from earlier utilization of allo-HCT after CAR-T therapy.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/3/20/3062/1502752/advancesadv2019000593.pdf

Reference20 articles.

1. Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia;Maude;N Engl J Med,2018

2. Axicabtagene ciloleucel CAR T-cell therapy in refractory large B-cell lymphoma;Neelapu;N Engl J Med,2017

3. Tisagenlecleucel in adult relapsed or refractory diffuse large B-cell lymphoma;Schuster;N Engl J Med,2019

4. CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients;Turtle;J Clin Invest,2016

5. Immunotherapy of non-Hodgkin’s lymphoma with a defined ratio of CD8+ and CD4+ CD19-specific chimeric antigen receptor-modified T cells;Turtle;Sci Transl Med,2016

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