Chronic lymphocytic leukemia increases the pool of peripheral blood hematopoietic stem cells and skews differentiation-Reference-Cited by-同舟云学术

Chronic lymphocytic leukemia increases the pool of peripheral blood hematopoietic stem cells and skews differentiation

Published:2020-12-18 Issue:24 Volume:4 Page:6310-6314
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Santoro Antonella¹^ORCID,Andrei Camelia²,Bryant Clare²^ORCID,Calderbank Emily¹,Wray Alison³,Baxter Joanna E.³^ORCID,Godfrey Anna²,Laurenti Elisa¹^ORCID,Ringshausen Ingo¹^ORCID

Affiliation:

1. Department of Haematology and Wellcome and MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom;

2. Haematopathology & Oncology Diagnostics Service, Department of Haematology Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom; and

3. Cambridge Blood and Stem Cell Biobank, University of Cambridge, United Kingdom

Abstract

Key Points CLL increases the pool of ST-HSCs in the peripheral blood. Differentiation of CLL-derived peripheral blood HSPCs is skewed toward the myeloid lineage.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/4/24/6310/1795611/advancesadv2020002863.pdf

Reference15 articles.

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4. Restoration of in vitro hematopoiesis in B-chronic lymphocytic leukemia by antibodies to tumor necrosis factor;Michalevicz;Leuk Res,1991

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