Glasdegib as maintenance therapy for patients with AML and MDS patients at high risk for postallogeneic stem cell transplant relapse-Reference-Cited by-同舟云学术

Glasdegib as maintenance therapy for patients with AML and MDS patients at high risk for postallogeneic stem cell transplant relapse

Published:2020-07-07 Issue:13 Volume:4 Page:3102-3108
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Kent Andrew¹,Vasu Sumithira²,Schatz Derek¹,Monson Natalie¹,Devine Steven²,Smith Clayton¹,Gutman Jonathan A.¹,Pollyea Daniel A.¹^ORCID

Affiliation:

1. Division of Hematology, School of Medicine, University of Colorado, Aurora, CO; and

2. James Cancer Center, The Ohio State University, Columbus, OH

Abstract

Key Points Posttransplantation, glasdegib maintenance therapy in patients at high risk for relapse did not meaningfully reduce relapse incidence. Use of glasdegib in the posttransplantation setting was complicated by adverse events requiring drug holds and occasional discontinuation.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/4/13/3102/1748081/advancesadv2020001991.pdf

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