Sequential allogeneic and autologous CAR-T–cell therapy to treat an immune-compromised leukemic patient-Reference-Cited by-同舟云学术

Sequential allogeneic and autologous CAR-T–cell therapy to treat an immune-compromised leukemic patient

Published:2018-07-19 Issue:14 Volume:2 Page:1691-1695
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Zhang Jian-Ping¹,Zhang Rui²,Tsao Shih-Ting²,Liu Yu-Chen²,Chen Xiaochuan²,Lu Dao-Pei¹,Castillo Paul³,Chang Lung-Ji²⁴⁵

Affiliation:

1. Beijing Lu Dao-Pei Hospital, Beijing, China;

2. Shenzhen Geno-immune Medical Institute, Shenzhen, China;

3. Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL;

4. University of Electronic Science and Technology of China, Sichuan, China; and

5. Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL

Abstract

Key Points CAR-T–cell therapy normally requires the patient’s own healthy T cells. An allogeneic CAR-T bridging therapy could rescue lymphopenic patients.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/14/1691/881026/advances017004.pdf

Reference20 articles.

1. Engineered T cells: the promise and challenges of cancer immunotherapy;Fesnak;Nat Rev Cancer,2016

2. Biology and clinical application of CAR T cells for B cell malignancies;Davila;Int J Hematol,2016

3. Chimeric antigen receptor T-cells for B-cell malignancies;Lichtman;Transl Res,2017

4. Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor;Kochenderfer;J Clin Oncol,2015

5. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial;Lee;Lancet,2015

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Advancement in “Off-the-Shelf” CAR T-Cell Therapy for Cancer Immunotherapy;Advances in Medical Diagnosis, Treatment, and Care;2024-08-28

2. Cytokine release syndrome after CAR T-cell therapy for B-cell acute lymphoblastic leukemia in children and young adolescents: storms make trees take deeper roots;Expert Opinion on Pharmacotherapy;2024-07-23

3. CAR-T CELL THERAPY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA;Mediterranean Journal of Hematology and Infectious Diseases;2024-01-01

4. 4SCAR2.0 therapy for the management of post-transplantation relapse of B-cell acute lymphoblastic leukemia;Frontiers in Hematology;2023-11-09

5. CD19 chimeric antigen receptor T cell therapy in leukemia xenograft mouse: Anti-leukemic efficacy, kinetics, and 4-week single-dose toxicity;Toxicology and Applied Pharmacology;2023-09