Ibrutinib in patients over 80 years old with CLL: a multicenter Italian cohort

Author:

Reda Gianluigi1ORCID,Mattiello Veronica1,Frustaci Anna Maria2ORCID,Visentin Andrea3ORCID,Mauro Francesca Romana4,Innocenti Idanna5,Gentile Massimo6,Giannarelli Diana7,Noto Alessandro1,Cassin Ramona1,Neri Antonino8,Laurenti Luca5ORCID,Tedeschi Alessandra2

Affiliation:

1. 1Hematology Unit, Fondazione Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

2. 2Department of Haematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy

3. 3Hematology and Clinical Immunology Unit, Department of Medicine, University of Padua, Padua, Italy

4. 4Hematology, Department of Translational and Precision Medicine, ‘Sapienza’ University, Rome, Italy

5. 5Dipartimento Scienze Radiologiche ed Ematologiche, Divisione di Ematologia Fondazione Policlinico universitario A Gemelli, Rome, Italy

6. 6Azienda Ospedaliera of Cosenza, Cosenza, Italy

7. 7Biostatistic Unit, Scientific Directorate, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy

8. 8Scientific Directorate Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy

Publisher

American Society of Hematology

Subject

Hematology

Reference25 articles.

1. iwCLL guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL;Hallek;Blood,2018

2. Ibrutinib in CLL/SLL: from bench to bedside (review);Zi;Oncol Rep,2019

3. Final analysis from RESONATE: up to six years of follow-up on ibrutinib in patients with previously treated chronic lymphocytic leukemia or small lymphocytic lymphoma;Munir;Am J Hematol,2019

4. Long-term efficacy and safety of first-line ibrutinib treatment for patients with CLL/SLL: 5 years of follow-up from the phase 3 RESONATE-2 study;Burger;Leukemia,2020

5. Ibrutinib for chronic lymphocytic leukemia with TP53 Alterations;Ahn;N Engl J Med,2020

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