CDX2 regulates ACE expression in blood development and leukemia cells-Reference-Cited by-同舟云学术

CDX2 regulates ACE expression in blood development and leukemia cells

Published:2021-04-12 Issue:7 Volume:5 Page:2012-2016
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

El Omar Reine¹^ORCID,Julien Emmanuelle¹,Biasch Katia¹²,Guffroy Blandine¹²³⁴⁵,Lioure Bruno³⁴,Vallat Laurent²⁵⁶^ORCID,Gross Isabelle²⁵,Domon-Dell Claire²⁵^ORCID,Lanza François¹^ORCID,Gachet Christian¹^ORCID,Negroni Matteo⁵⁷^ORCID,Freund Jean-Noël²⁵^ORCID,Tavian Manuela¹²⁵^ORCID

Affiliation:

1. Biologie et Pharmacologie des Plaquettes Sanguines (BPPS), Établissement Français du Sang Grand-Est, Unité Mixte de Recherche (UMR)-S1255, and

2. INSERM, Interface de Recherche Fondamentale et Appliquée en Cancérologie, UMR-S1113, Université de Strasbourg, Strasbourg, France;

3. Department of Hematology, University Hospital of Strasbourg, Strasbourg, France;

4. Institut de Cancérologie Strasbourg Europe, Strasbourg, France;

5. Interdisciplinary Thematic Institute (ITI) InnoVec, Strasbourg, France;

6. Laboratoire d’Hématologie, Pôle de Biologie, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; and

7. Centre National de la Recherche Scientifique, Architecture et Réactivité de l'ARN Unité Propre de Recherche 9002, Université de Strasbourg, Strasbourg, France

Abstract

Key PointsExpression of caudal-related homeobox gene 2 (CDX2) and angiotensin-converting enzyme (ACE) correlates during hematopoietic emergence. This emergence occurs in human and mouse embryos and in human acute myeloid leukemia; CDX2 homeoprotein also binds to the ACE promoter.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/5/7/2012/1804813/advancesadv2020003563.pdf

Reference25 articles.

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2. Angiotensin-converting enzyme (CD143) marks hematopoietic stem cells in human embryonic, fetal, and adult hematopoietic tissues;Jokubaitis;Blood,2008

3. Angiotensin-converting enzyme (CD143) specifies emerging lympho-hematopoietic progenitors in the human embryo;Sinka;Blood,2012

4. Renin-angiotensin system is involved in embryonic emergence of hematopoietic stem/progenitor cells [published online ahead of print 21 January 2021];Julien;Stem Cells

5. Physiology of local renin-angiotensin systems;Paul;Physiol Rev,2006

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