Adoptive T-cell therapy for pediatric cytomegalovirus-associated retinitis-Reference-Cited by-同舟云学术

Adoptive T-cell therapy for pediatric cytomegalovirus-associated retinitis

Published:2019-06-11 Issue:11 Volume:3 Page:1774-1777
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Seo Shiney¹^ORCID,Smith Corey²,Fraser Christopher³,Patheja Rajan¹,Shah Shaheen P.¹⁴,Rehan Sweera⁵,Crooks Pauline⁵,Neller Michelle A.⁵^ORCID,Khanna Rajiv⁵^ORCID

Affiliation:

1. Department of Ophthalmology, Queensland Children’s Hospital, South Brisbane, QLD, Australia;

2. Translational and Human Immunology Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia;

3. Blood and Marrow Transplant Service, Queensland Children’s Hospital, South Brisbane, QLD, Australia;

4. Department of Ophthalmology, The University of Queensland, St Lucia, QLD, Australia; and

5. Tumour Immunology Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia

Abstract

Key Points TCRαβ+/CD19+-depleted haploidentical HSCT was used to restore immunity in a pediatric patient with combined immunodeficiency syndrome. Posttransplant drug-resistant CMV retinitis was successfully treated with T cells expanded from a haploidentical HSCT donor.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/3/11/1774/1631803/advancesadv2019000121.pdf

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4. Assessment of cytomegalovirus-specific cell-mediated immunity for the prediction of cytomegalovirus disease in high-risk solid-organ transplant recipients: a multicenter cohort study;Manuel;Clin Infect Dis,2013

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