ABO blood group A transferases catalyze the biosynthesis of FORS blood group FORS1 antigen upon deletion of exon 3 or 4-Reference-Cited by-同舟云学术

ABO blood group A transferases catalyze the biosynthesis of FORS blood group FORS1 antigen upon deletion of exon 3 or 4

Published:2017-12-20 Issue:27 Volume:1 Page:2756-2766
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Yamamoto Miyako¹^ORCID,Cid Emili¹^ORCID,Yamamoto Fumiichiro¹²^ORCID

Affiliation:

1. Laboratory of Immunohematology and Glycobiology, Josep Carreras Leukaemia Research Institute, Campus Can Ruti, Barcelona, Spain; and

2. Programa de Medicina Predictiva i Personalitzada del Càncer, Institut d’Investigació Germans Trias i Pujol, Campus Can Ruti, Barcelona, Spain

Abstract

Key PointsABO blood group A transferases possess intrinsic FS activity upon deletion of exon 3 or 4 of A transferase messenger RNAs. Cointroduction of exon 3 or 4 deletion and GlyGlyAla substitution synergistically confers human A transferases with strong FS activity.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/1/27/2756/879249/advances009795.pdf

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