Serologic characterization of anti-protamine/heparin and anti-PF4/heparin antibodies-Reference-Cited by-同舟云学术

Serologic characterization of anti-protamine/heparin and anti-PF4/heparin antibodies

Published:2017-04-18 Issue:11 Volume:1 Page:644-651
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Lee Grace M.¹,Joglekar Manali¹,Kuchibhatla Maragatha²,Khandelwal Sanjay¹,Qi Rui¹,Rauova Lubica³⁴,Arepally Gowthami M.¹

Affiliation:

1. Division of Hematology and

2. Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC;

3. Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; and

4. Division of Hematology, Department of Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA

Abstract

Key Points Monoclonal and polyclonal anti-PRT/heparin antibodies are serologically distinct from anti-PF4/heparin antibodies. Binding of anti-PRT/heparin antibodies to PRT/dextran complexes correlates with PRT/GAG reactivity.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/1/11/644/877069/advances004408.pdf

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4. Drug-Induced Thrombocytopenia;Platelets;2019

5. Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway;BLOOD;2018