Macrophages and osteoclasts stem from a bipotent progenitor downstream of a macrophage/osteoclast/dendritic cell progenitor-Reference-Cited by-同舟云学术

Macrophages and osteoclasts stem from a bipotent progenitor downstream of a macrophage/osteoclast/dendritic cell progenitor

Published:2017-10-13 Issue:23 Volume:1 Page:1993-2006
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Xiao Yanling¹,Palomero Jara¹,Grabowska Joanna¹,Wang Liqin¹,de Rink Iris²,van Helvert Luuk¹,Borst Jannie¹

Affiliation:

1. Division of Immunology and

2. Genomics Core Facility, The Netherlands Cancer Institute–Antoni van Leeuwenhoek, Amsterdam, The Netherlands

Abstract

Key Points Under homeostatic conditions, MΦs, OCs, and DCs develop from a tripotent progenitor, the MODP. In mouse bone marrow, we define a novel, bipotent MΦ/OC progenitor, the MOP, that lies downstream of the MODP.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/1/23/1993/879047/advances008540.pdf

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