Prothrombin conversion is accelerated in the antiphospholipid syndrome and insensitive to thrombomodulin-Reference-Cited by-同舟云学术

Prothrombin conversion is accelerated in the antiphospholipid syndrome and insensitive to thrombomodulin

Published:2018-06-12 Issue:11 Volume:2 Page:1315-1324
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Kremers Romy M. W.¹²^ORCID,Zuily Stéphane³,Kelchtermans Hilde¹²,Peters Tessa C.¹²,Bloemen Saartje¹²^ORCID,Regnault Véronique³,Hemker H. Coenraad²^ORCID,de Groot Philip G.¹,Wahl Denis³,de Laat Bas¹²

Affiliation:

1. Synapse Research Institute and

2. Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, The Netherlands; and

3. Vascular Medicine Division, Centre Hospitalier Régional Universitaire de Nancy, Nancy, France

Abstract

Key PointsThe rate of prothrombin conversion is elevated in APS patients, causing a hemostatic imbalance. TG and prothrombin conversion are higher in APS patients with prior thrombosis than in patients without thrombosis.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/11/1315/882082/advances018036.pdf

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