Immunoglobulin isotype switch after anti-BCMA CAR T-cell therapy for relapsed or refractory multiple myeloma

Author:

Liang Zhiyu1ORCID,Li Ping1,Kang Liqing23,Zhou Lili1,Xu Yang4,Ye Shiguang1,Du Juan5ORCID,Li Bing1,Wang Yiwen6,Yu Lei23,Qian Wenbin4,Liang Aibin1

Affiliation:

1. Department of Hematology, Tongji Hospital of Tongji University, Shanghai, China;

2. Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China;

3. Shanghai Unicar-Therapy Bio-medicine Technology Co., Ltd, Shanghai, China;

4. Department of Hematology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China;

5. Department of Hematology, Myeloma & Lymphoma Center, Shanghai Changzheng Hospital, The Second Military Medical University, Shanghai, China; and

6. Shanghai World Foreign Language Academy, Shanghai, China

Publisher

American Society of Hematology

Subject

Hematology

Reference14 articles.

1. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma;Rajkumar;Lancet Oncol.,2014

2. Significance of abnormal protein bands in patients with multiple myeloma following autologous stem cell transplantation;Hall;Clin Biochem Rev.,2009

3. Isotype class switching after transplantation in multiple myeloma;Maisnar;Neoplasma.,2007

4. Oligoclonal protein bands and Ig isotype switching in multiple myeloma treated with high-dose therapy and hematopoietic cell transplantation;Zent;Blood.,1998

5. Clinical significance of the appearance of abnormal protein band in patients with multiple myeloma;Jo;Ann Hematol.,2014

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