Selectins and chemokines use shared and distinct signals to activate β2 integrins in neutrophils-Reference-Cited by-同舟云学术

Selectins and chemokines use shared and distinct signals to activate β2 integrins in neutrophils

Published:2018-03-28 Issue:7 Volume:2 Page:731-744
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Yago Tadayuki¹,Zhang Nan²,Zhao Liang³,Abrams Charles S.³,McEver Rodger P.¹²^ORCID

Affiliation:

1. Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK;

2. Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK; and

3. Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

Abstract

Key Points Selectin and chemokine signals use both Rap1a and PIP5Kγ90 to activate β2 integrins in neutrophils. Suboptimal chemokine signals synergize with selectin signals to activate β2 integrins in neutrophils.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/7/731/880684/advances015602.pdf

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