Cardiac and renal complications of carfilzomib in patients with multiple myeloma

Author:

Dimopoulos Meletios A.1ORCID,Roussou Maria1,Gavriatopoulou Maria1,Psimenou Erasmia1,Ziogas Dimitrios1,Eleutherakis-Papaiakovou Evangelos1,Fotiou Despina1,Migkou Magdalini1,Kanellias Nikolaos1,Panagiotidis Ioannis1,Ntalianis Argyrios1,Papadopoulou Elektra1,Stamatelopoulos Kimon1,Manios Efstathios1,Pamboukas Constantinos1,Kontogiannis Sofoklis1,Terpos Evangelos1,Kastritis Efstathios1ORCID

Affiliation:

1. Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

Abstract

Key Points Carfilzomib is associated with reversible cardiotoxicity in 12% of consecutive myeloma patients. Transient renal toxicity is common, but carfilzomib may improve renal function in myeloma-related renal impairment.

Publisher

American Society of Hematology

Subject

Hematology

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