Hematopoietic stem cell transplant for Hurler syndrome: does using bone marrow or umbilical cord blood make a difference?

Author:

Orchard Paul J.1ORCID,Gupta Ashish O.1ORCID,Eisengart Julie B.2ORCID,Polgreen Lynda E.3,Pollard Laura M.4,Braunlin Elizabeth5ORCID,Pasquali Marzia6,Lund Troy C.1ORCID

Affiliation:

1. 1Division of Pediatric Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN

2. 2Division of Clinical Behavioral Neuroscience, Department of Pediatrics, University of Minnesota, Minneapolis, MN

3. 3Los Angeles Biomedical Research Institute at Harbor-University of California, Los Angeles Medical Center, Torrance, CA

4. 4Biochemical Diagnostic Laboratory, Greenwood Genetic Center, Greenwood, SC

5. 5Department of Pediatrics, Division of Pediatric Cardiology, University of Minnesota, Minneapolis, MN

6. 6University of Utah, School of Medicine, Salt Lake City, UT

Publisher

American Society of Hematology

Subject

Hematology

Reference19 articles.

1. Hematopoietic stem cell transplantation in inborn errors of metabolism;Tan;Front Pediatr,2019

2. Haematopoietic cell transplantation (HCT) in combination with enzyme replacement therapy (ERT) in patients with Hurler syndrome;Cox-Brinkman;Bone Marrow Transplant,2006

3. Safety and efficacy of enzyme replacement therapy in combination with hematopoietic stem cell transplantation in Hurler syndrome;Grewal;Genet Med,2005

4. Microarray and serial analysis of gene expression analyses identify known and novel transcripts overexpressed in hematopoietic stem cells;Georgantas;Cancer Res,2004

5. Cord blood is the optimal graft source for the treatment of pediatric patients with lysosomal storage diseases: clinical outcomes and future directions;Aldenhoven;Cytotherapy,2015

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