Latent human cytomegalovirus enhances HIV-1 infection in CD34+ progenitor cells-Reference-Cited by-同舟云学术

Latent human cytomegalovirus enhances HIV-1 infection in CD34+ progenitor cells

Published:2017-01-16 Issue:5 Volume:1 Page:306-318
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Cheung Allen Ka Loon¹,Huang Yiru¹,Kwok Hau Yee¹,Chen Min¹²,Chen Zhiwei¹³

Affiliation:

1. AIDS Institute, Department of Microbiology, Research Center for Infection and Immunity, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China;

2. Yunnan Center for Disease Control and Prevention, Kunming, China; and

3. HKU AIDS Institute Shenzhen Research Laboratory and AIDS Clinical Research Laboratory, Guangdong Key Laboratory of Emerging Infectious Diseases and Shenzhen Key Laboratory of Infection and Immunity, Shenzhen Third People’s Hospital, Shenzhen, China

Abstract

Key PointsHCMV latency modulates host CD34+ cells in favoring HIV-1 infection. Latent HCMV upregulates HIV entry coreceptors and downregulates HIV restriction factors in CD34+ cells.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/1/5/306/878124/advances000638.pdf

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