Severely impaired terminal erythroid differentiation as an independent prognostic marker in myelodysplastic syndromes

Author:

Ali Abdullah Mahmood1,Huang Yumin23,Pinheiro Ronald Feitosa1,Xue Fumin2,Hu Jingping2,Iverson Nicholas1,Hoehn Daniela1,Coutinho Diego1,Kayani Jehanzeb1,Chernak Brian1,Lane Joseph4,Hillyer Christopher5,Galili Naomi1,Jurcic Joseph1,Mohandas Narla2,An Xiuli26,Raza Azra1

Affiliation:

1. Myelodysplastic Syndromes Center, Columbia University Medical Center, Columbia University, New York, NY;

2. Laboratory of Membrane Biology, New York Blood Center, New York, NY;

3. Department of Hematology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China;

4. Department of Orthopedic Surgery, New York Presbyterian Cornell Hospital, New York NY;

5. Laboratory of Red Cell Physiology, New York Blood Center, New York, NY; and

6. School of Life Science, Zhengzhou University, Zhengzhou, China

Abstract

Key Points TED is defective in patients with MDS. TED is an independent prognostic factor for survival in MDS.

Publisher

American Society of Hematology

Subject

Hematology

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