A user guide to the American Society of Hematology clinical practice guidelines

Author:

Izcovich Ariel1ORCID,Cuker Adam23ORCID,Kunkle Robert4,Neumann Ignacio56,Panepinto Julie7,Pai Menaka8,Seftel Matthew9,Cheung Matthew C.10,Lottenberg Richard11,Byrne Michael12,Plovnick Robert4,Terrell Deirdra13,Holter-Chakrabarty Jennifer L.14,Djulbegovic Benjamin1516,Hicks Lisa K.1718,Wiercioch Wojtek192021ORCID,Nieuwlaat Robby192021,Schünemann Holger J.8192021ORCID

Affiliation:

1. Department of Internal Medicine, German Hospital, Buenos Aires, Argentina;

2. Department of Medicine and

3. Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;

4. American Society of Hematology, Washington, DC;

5. Department of Internal Medicine and

6. Centro Evidencia UC, Pontificia Universidad Católica de Chile, Santiago, Chile;

7. Children’s of Wisconsin, Medical College of Wisconsin, Milwaukee, WI;

8. Department of Medicine, McMaster University, Hamilton, ON, Canada;

9. Department of Medicine, University of British Columbia, Vancouver, BC, Canada;

10. Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada;

11. Division of Hematology/Oncology, Department of Medicine, College of Medicine, University of Florida, Gainesville, FL;

12. Division of Hematology/Oncology, Department of Medicine, Vanderbilt University, Nashville, TN;

13. Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK;

14. Stephenson Cancer Center, Division of Hematology/Oncology/Transplantation and Cellular Therapy, Department of Medicine, University of Oklahoma, Oklahoma City, OK;

15. Department of Supportive Care Medicine and

16. Department of Hematology, City of Hope, Duarte, CA;

17. Department of Medicine, St. Michael’s Hospital, Toronto, ON, Canada;

18. Faculty of Medicine, University of Toronto, Toronto, ON, Canada; and

19. Michael G. DeGroote Cochrane Canada Centre,

20. McMaster GRADE Centre, and

21. Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada

Abstract

AbstractSince November 2018, Blood Advances has published American Society of Hematology (ASH) clinical practice guidelines on venous thromboembolism, immune thrombocytopenia, and sickle cell disease. More ASH guidelines on these and other topics are forthcoming. These guidelines have been developed using consistent processes, methods, terminology, and presentation formats. In this article, we describe how patients, clinicians, policymakers, researchers, and others may use ASH guidelines and the many related derivates by describing how to interpret information and how to apply it to clinical decision-making. Also, by exploring how these documents are developed, we aim to clarify their limitations and possible inappropriate usage.

Publisher

American Society of Hematology

Subject

Hematology

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