Induced pluripotent stem cell–based mapping of β-globin expression throughout human erythropoietic development-Reference-Cited by-同舟云学术

Induced pluripotent stem cell–based mapping of β-globin expression throughout human erythropoietic development

Published:2018-08-14 Issue:15 Volume:2 Page:1998-2011
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Vanuytsel Kim¹²^ORCID,Matte Taylor²,Leung Amy¹²,Naing Zaw Htut¹²,Morrison Tasha¹,Chui David H. K.¹^ORCID,Steinberg Martin H.¹^ORCID,Murphy George J.¹²^ORCID

Affiliation:

1. Section of Hematology and Medical Oncology, School of Medicine, Boston University, Boston, MA; and

2. Center for Regenerative Medicine (CReM), Boston University and Boston Medical Center, Boston, MA

Abstract

Key Points iPSC-derived definitive erythroid cells display a globin expression profile corresponding to yolk sac erythromyeloid progenitors. iPSC-derived erythroblasts resemble their postnatal counterparts in terms of gene expression and essential biological processes.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/15/1998/881382/advances020560.pdf

Reference58 articles.

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3. In vitro differentiation of Gata2 and Ly6a reporter embryonic stem cells corresponds to in vivo waves of hematopoietic cell generation;Kauts;Stem Cell Reports,2018

4. Distinct sources of ematopoietic progenitors emerge before HSCs and provide functional blood cells in the mammalian embryo;McGrath;Cell Reports,2015

5. Globin switches in yolk sac-like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells;Qiu;Blood,2008

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