TNP-470 skews DC differentiation to Th1-stimulatory phenotypes and can serve as a novel adjuvant in a cancer vaccine-Reference-Cited by-同舟云学术

TNP-470 skews DC differentiation to Th1-stimulatory phenotypes and can serve as a novel adjuvant in a cancer vaccine

Published:2018-07-16 Issue:14 Volume:2 Page:1664-1679
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Ho Derek Hoi-Hang¹²,Wong Roger Hoi-Fung¹

Affiliation:

1. Department of Biology, Hong Kong Baptist University, Hong Kong; and

2. Department of Chemistry, University of Hong Kong, Hong Kong

Abstract

Key Points TNP-470 skews DC differentiation to a phenotype with Th1-stimulatory features. TNP-470–treated DC vaccine protects mice from tumors by tumor-specific immunogenicity induction in prophylactic and therapeutic settings.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/14/1664/881074/advances013433.pdf

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