Postvaccination graft dysfunction/aplastic anemia relapse with massive clonal expansion of autologous CD8+ lymphocytes-Reference-Cited by-同舟云学术

Postvaccination graft dysfunction/aplastic anemia relapse with massive clonal expansion of autologous CD8+ lymphocytes

Published:2020-04-08 Issue:7 Volume:4 Page:1378-1382
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Ritz Caitlin¹²^ORCID,Meng Wenzhao³,Stanley Natasha L.¹²,Baroja Miren L.⁴,Xu Chong⁴,Yan Patrick⁴,Huang Alexander C.¹⁴^ORCID,Hausler Ryan¹,Nicholas Peter²,Fan Jian-Meng²,Lieberman David³,Carreno Beatriz M.³⁴,Luning Prak Eline T.³^ORCID,Olson Timothy S.²⁵,Babushok Daria V.¹²^ORCID

Affiliation:

1. Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA;

2. Comprehensive Bone Marrow Failure Center, Children’s Hospital of Philadelphia, Philadelphia, PA;

3. Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA;

4. Parker Institute for Cancer Immunotherapy and Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA; and

5. Division of Oncology, Department of Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA

Abstract

Key Points Acquired aplastic anemia is a T-cell–mediated autoimmune bone marrow aplasia, without a known etiologic trigger. Clonal expansion of CD8+ effector T lymphocytes can occur following vaccination and accompany graft dysfunction or aplastic anemia relapse.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/4/7/1378/1745584/advancesadv2019000853.pdf

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4. Severe pancytopenia triggered by recombinant hepatitis B vaccine;Viallard;Br J Haematol,2000

5. Pancytopenia after recombinant hepatitis B vaccine–an Indian case report;Ashok Shenoy;Br J Haematol,2001

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