Hispanic ethnicity is associated with younger age at presentation but worse survival in acute myeloid leukemia-Reference-Cited by-同舟云学术

Hispanic ethnicity is associated with younger age at presentation but worse survival in acute myeloid leukemia

Published:2017-10-26 Issue:24 Volume:1 Page:2120-2123
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Darbinyan Karine¹,Shastri Aditi²,Budhathoki Anjali²,Helbig Daniel³,Snyder Rose³,Pradhan Kith⁴,Saleh-Esa Junaid²,Kornblum Noah S.²,Binder Adam F.²,Goel Swati²,Janakiram Murali²,Derman Olga²,Gritsman Kira²,Steidl Ulrich²,Braunschweig Ira²,Verma Amit²,Mantzaris Ioannis²

Affiliation:

1. Department of Medicine, Jacobi Medical Center, Bronx, NY;

2. Department of Oncology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY;

3. Albert Einstein College of Medicine, Bronx, NY; and

4. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY

Abstract

Key Points SEER data and a Bronx validation cohort demonstrate that Hispanics present with AML at younger age but have shorter survival than whites. Increased frequency of high-risk mutations in Hispanics provides a potential biologic explanation for poorer outcomes in Hispanics.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/1/24/2120/879178/advances007013.pdf

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