Elevated RIPK3 correlates with disease burden in myelofibrosis

Author:

Dill Veronika123ORCID,Wagner Celina V.1ORCID,Keller Eva C.14ORCID,Fernandez-Hernandez Francisco Jose5,Shoumariyeh Khalid67,Odinius Timo O.1ORCID,Buschhorn Lars8,Hauch Richard T.9ORCID,Suren Christian10,Hecker Judith S.123ORCID,Herhaus Peter1,Sandherr Michael11,Schmidt Burkhard12,Slotta-Huspenina Julia4,Bassermann Florian1313,Höckendorf Ulrike1,Jilg Stefanie14,Branca Caterina1,Vosberg Sebastian5,Jost Philipp J.15

Affiliation:

1. 1Department of Internal Medicine III, School of Medicine, University hospital rechts der Isar, Technical University of Munich, Munich, Germany

2. 2German Cancer Consortium, Partner Site Munich, Munich, Germany

3. 3German Cancer Research Center, Heidelberg, Germany

4. 4Institute of Pathology, Technical University of Munich, Munich, Germany

5. 5Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

6. 6Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

7. 7German Cancer Consortium, Partner Site Freiburg, Freiburg, Germany

8. 8National Center for Tumor Diseases, Heidelberg, Germany

9. 9Pediatric Hematology and Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany

10. 10Department of Orthopedics and Sports Orthopedics, School of Medicine, University hospital rechts der Isar, Technical University of Munich, Munich, Germany

11. 11Gemeinschaftspraxis Hämato-Onkologie Weilheim, Weilheim, Germany

12. 12Gemeinschaftspraxis Hämato-Onkologie Pasing, Munich, Germany

13. 13Center for Translational Cancer Research (TranslaTUM), Technical University Munich, Klinikum rechts der Isar, Munich, Germany

14. 14Gemeinschaftspraxis Onkologie Erding, Erding, Germany

Publisher

American Society of Hematology

Subject

Hematology

Reference25 articles.

1. The critical role of inflammation in the pathogenesis and progression of myeloid malignancies;Craver;Cancers (Basel),2018

2. MPNs as inflammatory diseases: the evidence, consequences, and perspectives;Hasselbalch;Mediators Inflamm,2015

3. Cytokine regulation of microenvironmental cells in myeloproliferative neoplasms;Hoermann;Mediators Inflamm,2015

4. Dual implication of fibrogenic cytokines in the pathogenesis of fibrosis and myeloproliferation in myeloid metaplasia with myelofibrosis;Le Bousse-Kerdiles;Ann Hematol,1999

5. TNFalpha facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms;Fleischman;Blood,2011

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