Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation-Reference-Cited by-同舟云学术

Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation

Published:2018-03-13 Issue:5 Volume:2 Page:565-574
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

de Koning Coco¹,Gabelich Julie-Anne¹,Langenhorst Jurgen¹,Admiraal Rick¹²,Kuball Jurgen¹³,Boelens Jaap Jan¹²,Nierkens Stefan¹

Affiliation:

1. Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands;

2. Pediatric Blood and Marrow Transplantation Program, Wilhemina Children’s Hospital, Utrecht, The Netherlands; and

3. Department of Hematology, University Medical Center Utrecht, Utrecht, The Netherlands

Abstract

Key Points Residual ATG exposure delays CD4+ T-cell reconstitution more severely after CBT than after BMT. Filgrastim (G-CSF), given early after CBT, enhances ATG-mediated T-cell clearance in patients with residual ATG exposure.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/5/565/880491/advances015487.pdf

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