Epidemiology, clinical features, and outcome of HTLV-1–related ATLL in an area of prevalence in the United States-Reference-Cited by-同舟云学术

Epidemiology, clinical features, and outcome of HTLV-1–related ATLL in an area of prevalence in the United States

Published:2018-03-15 Issue:6 Volume:2 Page:607-620
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Malpica Luis¹^ORCID,Pimentel Agustin²,Reis Isildinha M.³,Gotuzzo Eduardo⁴,Lekakis Lazaros⁵⁶,Komanduri Krishna⁵⁶⁷,Harrington Thomas⁵,Barber Glen N.⁷⁸,Ramos Juan C.⁵⁷

Affiliation:

1. Internal Medicine Program, Jackson Memorial Hospital,

2. Division of Oncology, Department of Medicine, and

3. Division of Biostatistics, Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL;

4. Alexander von Humboldt Institute of Tropical Medicine and Infectious Diseases, Department of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru; and

5. Division of Hematology, Department of Medicine,

6. Adult Stem Cell Transplant Program,

7. Sylvester Comprehensive Cancer Center, and

8. Department of Cell Biology, University of Miami Miller School of Medicine, Miami, FL

Abstract

Key Points ATLL presents more aggressively in US Afro-Caribbean than Japanese patients and continues to have a poor outcome despite modern therapies. AZT-IFN is a reasonable up-front option for aggressive, nonbulky, leukemic ATLL subtypes, resulting in long PFS after a complete response.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/6/607/882693/advances011106.pdf

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