Urokinase plasminogen activator and receptor promote collagen-induced arthritis through expression in hematopoietic cells-Reference-Cited by-同舟云学术

Urokinase plasminogen activator and receptor promote collagen-induced arthritis through expression in hematopoietic cells

Published:2017-03-21 Issue:9 Volume:1 Page:545-556
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Thornton Sherry¹,Raghu Harini²,Cruz Carolina²,Frederick Malinda D.²,Palumbo Joseph S.³,Mullins Eric S.³,Almholt Kasper⁴,Usher Pernille A.⁴,Flick Matthew J.²

Affiliation:

1. Division of Rheumatology,

2. Division of Experimental Hematology, and

3. Division of Hematology, Cancer and Blood Diseases Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH; and

4. Global Research, Novo Nordisk A/S, Måløv, Denmark

Abstract

Key Points Deficiency in uPA or uPAR renders DBA/1 mice less susceptible to CIA. Expression of uPAR in bone marrow–derived cells promotes arthritis pathogenesis.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/1/9/545/878327/advances004002.pdf

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4. The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis;Li;Am J Pathol,2005

5. Amelioration of collagen-induced arthritis by thrombin inhibition;Marty;J Clin Invest,2001

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