Management of thrombotic thrombocytopenic purpura without plasma exchange: the Jehovah’s Witness experience

Author:

George James N.12ORCID,Sandler Steven A.3,Stankiewicz Joanna3

Affiliation:

1. Department of Medicine, College of Medicine, and

2. Department of Biostatistics and Epidemiology, College of Public Health, The University of Oklahoma Health Sciences Center, Oklahoma City, OK; and

3. Presence Resurrection Medical Center, Chicago, IL

Abstract

Key Points TTP in Jehovah’s Witness patients has been managed successfully without PEX. This experience, plus new TTP treatments, may make it possible for patients who are not Jehovah’s Witnesses to avoid PEX in the future.

Publisher

American Society of Hematology

Subject

Hematology

Reference19 articles.

1. Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura;Rock;N Engl J Med,1991

2. Committee for Hospital Information for Jehovah’s Witnesses. Religious and Ethical Position on Medical Therapy and Related Matters. https://www.jw.org/en/medical-library/strategies-downloads/religious-and-ethical-position-medical-therapy/. Accessed 8 October 2017.

3. ADAMTS13 content in plasma-derived factor VIII/von Willebrand factor concentrates;Peyvandi;Am J Hematol,2013

4. Successful treatment of congenital TTP with a novel approach using plasma-derived factor VIII;Naik;J Pediatr Hematol Oncol,2013

5. Successful management of a Jehovah’s Witness with thrombotic thrombocytopenic purpura unwilling to be treated with therapeutic plasma exchange;Dabak;J Clin Apher,2007

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