Successful treatment of thrombocytopenia with daratumumab after allogeneic transplant: a case report and literature review-Reference-Cited by-同舟云学术

Successful treatment of thrombocytopenia with daratumumab after allogeneic transplant: a case report and literature review

Published:2020-03-02 Issue:5 Volume:4 Page:815-818
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Migdady Yazan¹^ORCID,Ediriwickrema Asiri²,Jackson Ryan Patrick¹,Kadi Wendy¹,Gupta Ridhi³,Socola Francisco⁴,Arai Sally³^ORCID,Martin Beth A.²^ORCID

Affiliation:

1. Stanford University, Stanford, CA;

2. Division of Hematology, Stanford University School of Medicine, Stanford, CA;

3. Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University, Stanford, CA

4. Tulane University Medical Center, New Orleans, LA; and

Abstract

Key Points A source of treatment refractoriness in immune cytopenias appears to be residual CD138/38-positive lymphocyte populations. A short course of daratumumab is a novel treatment of refractory thrombocytopenia after failure of standard treatment options.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/4/5/815/1718757/advancesadv2019001215.pdf

Reference12 articles.

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3. B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells;Mahévas;J Clin Invest,2013

4. Persistence of recipient human leucocyte antigen (HLA) antibodies and production of donor HLA antibodies following reduced intensity allogeneic haematopoietic stem cell transplantation;Fasano;Br J Haematol,2014

5. Daratumumab is effective in the treatment of refractory post-transplant autoimmune hemolytic anemia: a pediatric case report;Tolbert;Blood,2016

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