TGF-β1 along with other platelet contents augments Treg cells to suppress anti-FVIII immune responses in hemophilia A mice-Reference-Cited by-同舟云学术

TGF-β1 along with other platelet contents augments Treg cells to suppress anti-FVIII immune responses in hemophilia A mice

Published:2016-11-30 Issue:2 Volume:1 Page:139-151
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Haribhai Dipica¹²³,Luo Xiaofeng⁴⁵,Chen Juan⁴,Jia Shuang¹²,Shi Linzheng⁴,Schroeder Jocelyn A.¹²³⁴,Weiler Hartmut⁴,Aster Richard H.⁴,Hessner Martin J.¹²,Hu Jianda⁵,Williams Calvin B.¹²³,Shi Qizhen¹²³⁴

Affiliation:

1. Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI;

2. Children’s Research Institute, Children’s Hospital of Wisconsin, Milwaukee, WI;

3. Midwest Athletes Against Childhood Cancer Fund Research Center, Milwaukee, WI;

4. Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI; and

5. Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fuzhou, China

Abstract

Key Points TGF-β1 from unfractionated pltLys can efficiently induce Treg cells. The properties of Treg cells induced by TGF-β1 are altered by platelet contents.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/1/2/139/877652/advances001453.pdf

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