In silico prediction of nonpermissive HLA-DPB1 mismatches in unrelated HCT by functional distance-Reference-Cited by-同舟云学术

In silico prediction of nonpermissive HLA-DPB1 mismatches in unrelated HCT by functional distance

Published:2018-07-24 Issue:14 Volume:2 Page:1773-1783
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Arrieta-Bolaños Esteban¹^ORCID,Crivello Pietro¹,Shaw Bronwen E.²,Ahn Kwang Woo²,Wang Hai-Lin²,Verneris Michael R.³,Hsu Katharine C.⁴,Pidala Joseph⁵,Lee Stephanie J.²⁶,Fleischhauer Katharina¹,Spellman Stephen R.⁷

Affiliation:

1. Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany;

2. Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI;

3. Pediatric Bone Marrow Transplantation, University of Colorado, Aurora, CO;

4. Memorial Sloan Kettering Cancer Center, New York, NY;

5. Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL;

6. Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA; and

7. Center for International Blood and Marrow Transplant Research, Minneapolis, MN

Abstract

Key Points Nonpermissive T-cell epitope group mismatches can be predicted in silico for any HLA-DPB1 allele by functional distance scores. In silico–predicted nonpermissive DPB1 mismatches are associated with mortality and GVHD after 8/8 matched HCT.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/14/1773/881174/advances019620.pdf

Reference68 articles.

1. Allo-reactive T cells for the treatment of hematological malignancies;Falkenburg;Mol Oncol,2015

2. HLA mismatching as a strategy to reduce relapse after alternative donor transplantation;Fleischhauer;Semin Hematol,2016

3. Graft-versus-host disease versus graft-versus-leukemia;Negrin;Hematology Am Soc Hematol Educ Program,2015

4. The IPD and IMGT/HLA database: allele variant databases;Robinson;Nucleic Acids Res,2015

5. A proposed algorithm predictive for cytotoxic T cell alloreactivity;Jöris;J Immunol,2012

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