1. From the Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI; the Greenebaum Cancer Center at the University of Maryland, Baltimore, MD; the New England Medical Center, Tufts University School of Medicine, Boston, MA; the University of Chicago, Chicago, IL; Massachusetts General Hospital, Brigham and Women's Hospital (Dana Farber Cancer Institute) at Harvard Medical School, Cambridge, MA; and Amgen Inc, Thousand Oaks, CA.