1. From the Third Department of Internal Medicine and Department of Cell Therapy and Transplantation Medicine, Faculty of Medicine, University of Tokyo, Tokyo Japan; Departments of Biology, Human Genetics, and Medicine, Yale University, New Haven, CT; Division of Hematology, Department of Internal Medicine, New York University Medical Center, New York, NY; and Fujisaki Cell Center, Hayashibara Biochemical Research Laboratories, Okayama, Japan.