A Syndrome Resembling Adrenal Cortical Insufficiency Associated with Long Term Busulfan (Myleran) Therapy-Reference-Cited by-同舟云学术

A Syndrome Resembling Adrenal Cortical Insufficiency Associated with Long Term Busulfan (Myleran) Therapy

Published:1961-11-01 Issue:5 Volume:18 Page:497-510
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

KYLE ROBERT A.¹²,SCHWARTZ ROBERT S.¹³,OLINER HERMAN L.¹²,DAMESHEK WILLIAM¹⁴

Affiliation:

1. Blood Research Laboratory, Pratt Clinic—New England Center Hospital, and the Department of Medicine, Tufts University School of Medicine, Boston, Mass.

2. Blood Research Laboratory, New England Center Hospital, Boston, Mass.

3. Blood Research Laboratory, New England Center Hospital, and Assistant Professor of Medicine, Tufts University School of Medicine, Boston, Mass.

4. Blood Research Laboratory, New England Center Hospital, and Professor of Mcdicine, Tufts University School of Medicine, Boston, Mass.

Abstract

Abstract Four patients who developed a clinical syndrome characterized by hyperpigmentation of the skin, weakness, fatigue, weight loss, anorexia and nausea while on long-term treatment with busulfan were described. The etiology of the disorder, although clearly related to the busulfan therapy, is obscure, but may be related to "dethiolation".

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/18/5/497/570278/497.pdf

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