Long-term health-related quality of life evaluated more than 20 years after hematopoietic stem cell transplantation for thalassemia

Author:

La Nasa Giorgio12,Caocci Giovanni12,Efficace Fabio3,Dessì Carlo4,Vacca Adriana1,Piras Eugenia1,Sanna Marco1,Marcias Michela4,Littera Roberto5,Carcassi Carlo56,Lucarelli Guido7

Affiliation:

1. Bone Marrow Transplant Center, R. Binaghi Hospital, Cagliari, Italy;

2. Hematology Unit, Department of Medical Sciences “Mario Aresu,” University of Cagliari, Italy;

3. Health Outcomes Research Unit, Italian Group for Adult Hematologic Diseases Data Center, Rome, Italy;

4. Department of Clinic and Biology of Developmental Age, Second Institute of Pediatrics, Regional Hospital for Microcytemia, Cagliari, Italy;

5. Regional Transplant Center, R. Binaghi Hospital, Cagliari, Italy;

6. Medical Genetics, Department of Medical Sciences “Mario Aresu,” University of Cagliari, Italy; and

7. Istituto Mediterraneo di Ematologia Foundation, Mediterranean Institute of Hematology, University of Tor Vergata, Rome, Italy

Abstract

Key Points HRQoL and lifestyles of patients transplanted more than 20 years ago for thalassemia are similar to those of the general population. Data on HRQoL in the long term provide both physicians and patients with a more complete picture of the advantages and potential risks of HSCT.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference44 articles.

1. Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine.;Borgna-Pignatti;Haematologica,2004

2. Surviving with thalassemia major: the Italian experience.;Borgna-Pignatti;Pediatr Hematol Oncol,2007

3. β-thalassemia.;Rund;N Engl J Med,2005

4. Marrow transplantation for thalassaemia.;Thomas;Lancet,1982

5. Allogeneic marrow transplantation for thalassemia.;Lucarelli;Exp Hematol,1984

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